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Science 3 July 1959:
Vol. 130. no. 3366, pp. 40 - 41
DOI: 10.1126/science.130.3366.40
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Articles

Nature of Colchicine Resistance in Golden Hamster

A. REES MIDGLEY 1, BARRY PIERCE 1, and FRANK J. DIXON 1

1 Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

The unresponsiveness of the golden hamster to colchicine has been shown to be the result of a resistance of individual cells to the drug. This resistance makes it possible to use hamsters with heterotransplanted tumors for testing the in vivo effects of colchicine on the tumors, with no toxic host reactions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Methylmercury-induced Cytogenetic Damage in Syrian Hamster Bone Marrow Cells.
J. B. Mailhes (1984)
International Journal of Toxicology 3, 295-301
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Rheumatism and Arthritis: Review of American and English Literature of Recent Years * (Fourteenth Rheumatism Review).
C. J. SMYTH, R. L. BLACK, C. L. CHRISTIAN, E. P. ENGLEMAN, E. C. FRANKLIN, D. F. HILL, J. L. HOLLANDER, H. L. HOLLEY, J. G. MAYNE, W. M. MIKKELSEN, et al. (1962)
Ann Intern Med 56, 1-152
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)