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Science 15 May 1959:
Vol. 129. no. 3359, pp. 1366 - 1367
DOI: 10.1126/science.129.3359.1366
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Articles

Prolongation of Response of Node of Ranvier by Metal Ions

C. S. SPYROPOULOS 1 and R. O. BRADY 1

1 National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Maryland

The response of the node of Ranvier can be prolonged up to 5 to 6 seconds by addition to the medium of minute amounts of certain metal ions. This prolongation involves a change from a triangular to a rectangular configuration. The properties of the prolonged nerve-fiber responses are very similar to those of heart muscle.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)