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Science 13 February 1959:
Vol. 129. no. 3346, pp. 393 - 394
DOI: 10.1126/science.129.3346.393

Articles

Second Spectroscopically Abnormal Methemoglobin Associated with Hereditary Cyanosis

PARK S. GERALD 1 and PHILIP GEORGE 2

1 Department of Pediatrics, Harvard Medical School, and Children's Medical Center, Boston, Massachusetts
2 John Harrison Laboratory of Chemistry, University of Pennsylvania, Philadelphia

Isolation of an abnormal methemoglobin from two families exhibiting dominantly transmitted cyanosis have permitted the recognition of two different pigments of the hemoglobin M type. It is possible that the abnormal properties which characterize the acidic methemoglobin derivatives result from a crevice configuration of the heme, with two Feprotein bonds.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Hereditary Diaphorase Deficiency and Methemoglobinemia.
M. CAWEIN, C. H. BEHLEN II, E. J. LAPPAT, and J. E. COHN (1964)
Arch Intern Med 113, 578-585
   Abstract »    PDF »
Congenital Methemoglobinemia in Pregnancy.
G. Pepper, H. G. Weinstein, and P. Heller (1961)
JAMA 177, 328-330
   Abstract »    PDF »
SOME LESSONS FROM THE RED BLOOD CELL.
L. E. YOUNG (1960)
Ann Intern Med 53, 924-935
   Abstract »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)