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Science 13 February 1959:
Vol. 129. no. 3346, pp. 391 - 392
DOI: 10.1126/science.129.3346.391
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Articles

Continuous Protein Synthesis in Nuclei, Shown by Radioautography with H3-Labeled Amino Acids

J. CARNEIRO 1 and C. P. LEBLOND 1

1 Department of Anatomy, McGill University, Montreal, Canada

Radioautographic investigation of the cell nuclei of adult mice after injection of leucine-H3, methionine-H3, or glycine-H3 shows a high uptake of tritium by chromatin material but not by nucleoli. It is concluded that protein synthesis occurs continuously within nuclear chromatin.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)