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Science 30 January 1959:
Vol. 129. no. 3344, pp. 270 - 271
DOI: 10.1126/science.129.3344.270
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Articles

Ammonia Excretion by Mammalian Lung

EUGENE D. ROBIN 1, DAVID M. TRAVIS 1, PHILIP A. BROMBERG 1, CLAUDE E. FORKNER JR. 1, and JOHN M. TYLER 1

1 Department of Medicine, Harvard Medical School, and Medical Clinics, Peter Bent Brigham Hospital, Boston, Massachusetts

The intravenous administration of ammonium acetate to dogs results in measurable levels of free ammonia in expired air. Simultaneous measurement of the physiologic dead space permits the calculation of the partial pressure of ammonia in alveolar air. This finding has implications for ammonium metabolism and transport.


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Am J Physiol Lung Cell Mol Physiol 297, L153-L163
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