Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 23 January 1959:
Vol. 129. no. 3343, p. 212
DOI: 10.1126/science.129.3343.212
Prev | Table of Contents | Next

Articles

Fibrillation and Potassium Influx

W. C. HOLLAND 1 and A. H. BRIGS 1

1 Department of Pharmacology, Vanderbilt Medical School, Nashville, Tennessee

Absolute influx and efflux of potassium-42 have been measured in isolated rabbit atria during acetylcholine-induced fibrillation. The efflux of potassium was increased three to four times; influx was not changed. The data are interpreted as indicating that an inhibition of active K uptake is not involved in the initiation of fibrillation, and that the process results from a marked increase in Na permeability.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)