Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 14 November 1958:
Vol. 128. no. 3333, pp. 1208 - 1209
DOI: 10.1126/science.128.3333.1208
Prev | Table of Contents | Next

Articles

Property of Cerebrospinal Fluid Associated with Disturbed Metabolism of Central Nervous System

LORING F. CHAPMAN 1 and HAROLD G. WOLFF 1

1 Departments of Medicine and Psychiatry, New York Hospital-Cornell Medical Center, New York

Cerebrospinal fluid was assayed for the capacity to contract smooth muscle and for the capacity to develop such activity when incubated with globulin. Activity was observed in fluid collected from patients with inflammatory or degenerative disease of the central nervous system, sustained intracranial vasodilatation, sustained noxious stimulation, or chronic schizophrenia. Control specimens lacked measurable activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Neurohumoral Features of Afferent Fibers in Man: Their Role in Vasodilatation, Inflammation, and Pain.
L. F. CHAPMAN, A. O. RAMOS, H. GOODELL, and H. G. WOLFF (1961)
Arch Neurol 4, 617-650
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)