Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 29 June 1945:
Vol. 101. no. 2635, pp. 665 - 668
DOI: 10.1126/science.101.2635.665
Prev | Table of Contents | Next

Articles

A SEARCH FOR VIRUS-INACTIVATING SUBSTANCES AMONG MICROORGANISMS

DORIS JONES 1, F. R. BEAUDETTE 1, WALTON B. GEIGER 1, and SELMAN A. WAKSMAN 1

1 DEPARTMENTS OF MICROBIOLOGY AND POULTRY SCIENCE, NEW JERSEY AGRICULTURAL EXPERIMENT STATION, RUTGERS UNIVERSITY

One hundred and fifty organisms, comprising bacteria, fungi and actinomycetes, were isolated from straw-compost, manure, soil, drainage material and soil enriched with virus concentrates, and were tested for antiviral activity in vitro. Three of these organisms gave indications of possible inactivation of some of the fowl pox virus, and, in one case, of the laryngotracheitis virus. The active principle of one of these organisms was actinomycin A, an antibacterial substance known to be highly toxic to animals. The other two organisms were less extensively studied, and no claims regarding their antiviral potentialities can be made at present.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
INFECTIOUS DISEASES: ELEVENTH ANNUAL REVIEW OF SIGNIFICANT PUBLICATIONS.
H. A. REIMANN (1945)
Arch Intern Med 76, 114-129
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)