# Preparing Manuscripts using LaTeX

For quickest processing, we prefer to receive final manuscripts from authors in Word docx format. If you wish to use LaTeX, please observe the guidelines on this page in setting up your paper. Make sure that your PDF files are legible on the computer screen to avoid delays in processing.

Initial submission: To prepare your manuscript in LaTeX, please follow the LaTeX source guidelines below. Generate PDF files for the main text and Supplementary Materials, and upload them in the “Manuscript” and “Supplementary Materials” sections of the “Manuscript Documents” tab. The figures should be included in the PDF files; do not upload them separately at this stage (see the section on Figures in the LaTeX source guidelines below).

Revision: To prepare your manuscript in LaTeX, please follow the LaTeX source guidelines below. Generate PDF files for the main text and Supplementary Materials, and upload them in the “Manuscript” and “Supplementary Materials” sections of the “Manuscript Documents” tab. At this stage, the main text file should not include figures but should include their captions (see the section on Figures in the LaTeX source guidelines below). The Supplementary Materials pdf file should include figures. Upload the main text figures in the “Figures” section of the “Manuscript Documents” tab. In addition, in the “Auxiliary Supplementary Materials and Other Supporting Files” section of the “Manuscript Documents” tab, please upload a zip archive of your LaTeX files for the main text, consisting of your .tex, .aux, and .pdf files.

LaTeX source guidelines

1. Use LaTeX2e. Manuscripts should be marked up in LaTeX2e, not LaTeX 2.09 or any earlier release.
2. Keep it simple.
• Keep your LaTeX files as simple as possible; do not use elaborate local macros or highly customized style files. Please use the simple scifile.tex template for formatting your paper.
• Prepare only one .tex file; do not use \include or \input to incorporate another source file
• Do not use external style files, except for those already called out in the scifile.tex template. If you need additional macros, please keep them simple and include them in the actual .tex document preamble.
• Source code should be set up so that all .sty and .bst files called by the main .tex file are in the same directory as the main .tex file.
• Avoid using AMS-LaTeX or other specialized macros for generating math.
• Simple (i.e., non-nested) tables can be generated using the {tabular} environment. For nested tables, you may want to generate the table using a word processor and send it as a separate file.
3. References. Include references as an itemized list in your .tex file (see the scifile.tex template). If you are using BibTeX, do not submit .bib and .bbl files. Instead, compile your LaTeX  and copy the contents of the generated .bbl file into your .tex file. Science bibliography style file is available here: Science.bst
4. Use only the generic \cite{} command for referencing in the text, not other commands built on special macros. Also, make sure that there is no space between reference keynames within the braces (i.e., \cite{refone,reftwo,refthree}, not\cite{refone, reftwo, refthree}).
1. Figures. How to handle figures depends on whether your manuscript is an initial submission or submission of a revised version after peer review.
1. If the manuscript is an initial submission, you should include figures within the PDF file that you upload, preferably at the end of the text. You can accomplish this by simply appending the figures to the end of the PDF file (using Acrobat or another utility) or by including commands in your source file to insert graphics.
2. For the final, revised draft (i.e., after peer review), do not include commands in your source file to insert PostScript or other graphics. Instead, generate figure captions at the end of your LaTeX file as ordinary text (i.e., do not use the {figure} environment). Save your figures as separate files, using Science's guidelines for preparing figures, and upload the figures separately.
2. Compilation. Compile your LaTeX as many times as necessary to get a clean compilation. For those not using BibTeX, two compiles should do the trick; those using BibTeX should run the standard LaTeX --> BibTeX --> LaTeX --> LaTeX sequence. Be sure to save the .aux and .bbl files generated by the compilation.